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Naphazoline hydrochloride

Product #: TL1016
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l  General Information

Product Name

Naphazoline HCl

General description

Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.

Synonym

2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole; hydrochloride

Purity

≥98.0%(HPLC)

CAS Number

550-99-2

Formula

C14H15ClN2

Molecular Weight

246.738

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Off White solid

Solubility(25°C)

DMSO

≥5mg/mL

Ethanol

≥15mg/mL

Water

≥35mg/mL

l  Biological Information

Biochem/Physiol  Actions

Naphazoline Hydrochloride is the hydrochloride salt form of naphazoline, an imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive properties. Upon ocular administration, naphazoline hydrochloride exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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