l General Information |
Product Name | Danazol |
General description | Danazol is a synthetic androgen derived from ethinyl testosterone. |
Synonym | WIN-17757; 2,3-Isoxazolethisterone |
Purity | ≥98.5%(HPLC) | CAS Number | 17230-88-5 |
Formula | C22H27NO2 | Molecular Weight | 337.46 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Very slightly soluble |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | ≥25mg/mL |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Danazol is a derivative of the synthetic steroid ethisterone, a modified testosterone. It was approved by the U.S. Food and Drug Administration (FDA) as the first drug to specifically treat endometriosis, but its role as a treatment for endometriosis has been largely replaced by the gonadotropin-releasing hormone (GnRH) agonists. Danazol has antigonadotropic and anti-estrogenic activities. Danazol acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not
for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
