l General Information |
Product Name | Nutlin-3a |
General description | Nutlin-3a is the active enantiomer of
Nutlin-3. |
Synonym | (-)-Nutlin-3 |
Purity | ≥98.0%(HPLC) | CAS Number | 675576-98-4 |
Formula | C30H30Cl2N4O4 | Molecular Weight | 581.494 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | ≥50mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | Nutlin-3a, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for
drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
