l General Information |
Product Name | KU-55933 |
General description | KU-55933 is a potent and specific ATM inhibitor. |
Synonym | 2-morpholin-4-yl-6-thianthren-1-ylpyran-4-one |
Purity | ≥97%(HPLC) | CAS Number | 587871-26-9 |
Formula | C21H17NO3S2 | Molecular Weight | 395.491 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Light yellow solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | KU-55933 is a potent and specific ATM inhibitor with IC50/Ki of 12.9 nM/2.2 nM in cell-free assays, and is highly selective for ATM as compared to DNA-PK, PI3K/PI4K, ATR and mTOR. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not
for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
