l General Information |
Product Name | Edaravone |
General description | Edaravone is a novel potent free radical scavenger that has been clinically used to reduce the neuronal damage following ischemic stroke. |
Synonym | 5-methyl-2-phenyl-4~{H}-pyrazol-3-one; MCI-186 |
Purity | ≥98%(HPLC) | CAS Number | 89-25-8 |
Formula | C10H10N2O | Molecular Weight | 174.2 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Beige or light brownish yellow solid |
Solubility(25°C) | DMSO | ≥30mg/mL |
Ethanol | ≥30mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | Edaravone scavenges free hydroxyl radicals and peroxynitrite radicals which are highly associated with neuronal damage/death from many cerebral vascular disorders such as ischemic strokes and degenerative neurological disorders such as ALS. It exerts a neuroprotective and antioxidant effect and delays disease progression by limiting the extent of lipid peroxidation via free radical generation and cell membrane damage from oxidative stress. It reversed the reduction in regional blood flow and cerebral edema in a case of ischemic stroke. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not
for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
