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Lidocaine

Product #: TL0902
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Details

l  General Information

Product Name

Lidocaine

General description

Lidocaine is an anesthetic agent indicated for production of local or regional anesthesia.

Synonym

Alphacaine; 2-(diethylamino)-~{N}-(2,6-dimethylphenyl)acetamide

Purity

≥98%(HPLC)

CAS Number

137-58-6

Formula

C14H22N2O

Molecular Weight

234.34

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White solid

Solubility(25°C)

DMSO

≥45mg/mL

Ethanol

≥45mg/mL

Water

≥5mg/mL

l  Biological Information

Biochem/Physiol  Actions

Lidocaine  is an anesthetic agent indicated for production of local or regional anesthesia and in the treatment of ventricular tachycardia occurring during cardiac manipulation, such as surgery or catheterization, or which may occur during acute myocardial infarction, digitalis toxicity, or other cardiac diseases. The mode of action of the antiarrhythmic effect of Lidocaine appears to be similar to that of procaine, procainamide and quinidine. Ventricular excitability is depressed and the stimulation threshold of the ventricle is increased during diastole. The sinoatrial node is, however, unaffected. In contrast to the latter 3 drugs, Lidocaine in therapeutic doses does not produce a significant decrease in arterial pressure or in cardiac contractile force. In larger doses, lidocaine may produce circulatory depression, but the magnitude of the change is less than that found with comparable doses of procainamide.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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