l General Information |
Product Name | Bicalutamide |
General description | Bicalutamide is a synthetic, nonsteroidal antiandrogen. |
Synonym | ~{N}-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methylpropanamide; Casodex; Cosudex; Calutide |
Purity | ≥99.0%(HPLC) | CAS Number | 90357-06-5 |
Formula | C18H14F4N2O4S | Molecular Weight | 430.374 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White solid |
Solubility(25℃) | DMSO | ≥25mg/mL |
Ethanol | ≥5mg/mL |
Water | Insolube |
l Biological Information |
Biochem/Physiol
Actions | Bicalutamide is a synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This
product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
