Product Name

Indoleacetic Acid

Synonym

2-(1H-indol-3-yl)acetic acid; Indole-3-acetic acid 3-Indoleacetic acid; Heteroauxin

Purity

≥98.0%(HPLC)

CAS Number

87-51-4

Formula

C¹⁰H⁹NO²

Molecular Weight

175.187

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or beige to light pink solid

Solubility(25℃)

DMSO

≥25mg/mL

Ethanol

≥mg/mL

Water

≥mg/mL

l  Biological Information

Biochem/Physiol  Actions

Indoleacetic acid (IAA) is a breakdown product of tryptophan metabolism and is often produced by the action of bacteria in the mammalian gut. Some endogenous production of IAA in mammalian tissues also occurs. It may be produced by the decarboxylation of tryptamine or the oxidative deamination of tryptophan. IAA frequently occurs at low levels in urine and has been found in elevated levels in the urine of patients with phenylketonuria. Using material extracted from human urine, it was discovered by Kogl in 1933 that Indoleacetic acid is also an important plant hormone. Specifically IAA is a member of the group of phytohormones called auxins. IAA is generally considered to be the most important native auxin. Plant cells synthesize IAA from tryptophan. IAA and some derivatives can be oxidised by horseradish peroxidase (HRP) to cytotoxic species. IAA is only toxic after oxidative decarboxylation; the effect of IAA/HRP is thought to be due in part to the formation of methylene-oxindole, which may conjugate with DNA bases and protein thiols. IAA/HRP could be used as the basis for targeted cancer, a potential new role for plant auxins in cancer therapy.

Application

Plant Growth Regulators

l  Storage

Storage temp.

0-5℃

l  Precautions and Disclaimer

This  product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov