l General Information |
Product Name | Quinine Bisulfate |
General description | Quinine bisulfate is an alkaloid derived from the bark of the cinchona tree. |
Synonym | (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid |
Purity | ≥99.0%(HPLC) | CAS Number | 549-56-4 |
Formula | C20H26N2O6S | Molecular Weight | 422.496 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White solid |
Solubility(25℃) | DMSO | ≥25mg/mL |
Ethanol | ≥mg/mL |
Water | ≥25mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Quinine bisulfate is the sulfate salt form of the quinidine alkaloid isolate quinine. Quinine has many mechanisms of action, including reduction of oxygen intake and carbohydrate metabolism; disruption of DNA replication and transcription via DNA intercalation; and reduction of the excitability of muscle fibers via alteration of calcium distribution. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. |
Application | 1. Analgesics, Non-Narcotic 2. Antimalarials 3. Muscle Relaxants, Central |
l Storage |
Storage temp. | 2-8℃ |
l Precautions and Disclaimer |
This
product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
