l General Information |
Product Name | DL-Dihydroorotic acid |
General description | DL-Dihydroorotic acid is a substrate of the enzyme orotate reductase, which is part of the pyrimidine metabolism pathway. |
Synonym | 4, 5-Dihydroorotic acid |
Purity | ≥98.0%(TLC) | CAS Number | 6202-10-4 |
Formula | C5H6N2O4 | Molecular Weight | 158.11 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White solid |
Solubility(25℃) | DMSO | ≥10mg/mL |
Water | Slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | 4, 5-Dihydroorotic acid is a substrate of
the enzyme orotate reductase [EC 1. 3. 1. 14], which is part of the pyrimidine metabolism pathway. (KEGG) Dihydroorotate is oxidized by Dihydroorotate dehydrogenases (DHODs) to orotate. These dehydrogenases use their FMN (flavin mononucleotide) prosthetic group to abstract a hydride equivalent from C6 to deprotonate C5. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This
product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
