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Antipyrine

Product #: TL0865
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Details

l  General Information

Product Name

Antipyrine

General description

Antipyrine is an analgesic and antipyretic agent; selective COX-3 inhibitor.

Synonym

1,5-dimethyl-2-phenylpyrazol-3-one; Phenazone; Antipyrin; Phenazon; Analgesine

Purity

≥99.0%(HPLC)

CAS Number

60-80-0

Formula

C11H12N2O

Molecular Weight

188.23

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White solid

Solubility(25℃)

DMSO

≥25mg/mL

Ethanol

≥25mg/mL

Water

≥25mg/mL

l  Biological Information

Biochem/Physiol   Actions

Metabolite Description from Human Metabolome Database (HMDB)

Antipyrine is a pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at C-1 and C-5 and with a phenyl group at N-2. It has a role as a non-narcotic analgesic, an antipyretic, a non-steroidal anti-inflammatory drug, an opioid analgesic, a cyclooxygenase 3 inhibitor, a xenobiotic and an environmental contaminant.

Antipyrine is an analgesic and antipyretic agent; selective COX-3 inhibitor.

Application

Antipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.

l  Storage

Storage temp.

0-5℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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