l General Information |
Product Name | Antipyrine |
General description | Antipyrine is an analgesic and antipyretic agent; selective COX-3 inhibitor. |
Synonym | 1,5-dimethyl-2-phenylpyrazol-3-one; Phenazone; Antipyrin; Phenazon; Analgesine |
Purity | ≥99.0%(HPLC) | CAS Number | 60-80-0 |
Formula | C11H12N2O | Molecular Weight | 188.23 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White solid |
Solubility(25℃) | DMSO | ≥25mg/mL |
Ethanol | ≥25mg/mL |
Water | ≥25mg/mL |
l Biological Information |
Biochem/Physiol Actions | Metabolite Description from Human Metabolome Database (HMDB) Antipyrine is a pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at C-1 and C-5 and with a phenyl group at N-2. It has a role as a non-narcotic analgesic, an antipyretic, a non-steroidal anti-inflammatory drug, an opioid analgesic, a cyclooxygenase 3 inhibitor, a xenobiotic and an environmental contaminant. Antipyrine is an analgesic and antipyretic agent; selective COX-3 inhibitor. |
Application | Antipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. |
l Storage |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |