Product Name

Inosine

General description

Inosine is a purine nucleoside that has hypoxanthine ed by the N9 nitrogen to the C1 carbon of ribose.

Synonym

Hypoxanthosine; Ribonosine; Atorel

Purity

≥99.0%(HPLC)

CAS Number

58-63-9

Formula

C¹⁰H¹²N⁴O⁵

Molecular Weight

268.229

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Very slightly soluble

Water

≥40mg/mL

l  Biological Information

Biochem/Physiol   Actions

Inosine is a purine nucleoside that has hypoxanthine ed by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules.Inosine is found to be associated with purine nucleoside phosphorylase deficiency and xanthinuria type I, which are inborn errors of metabolism.

Inosine is a purine nucleoside in which hypoxanthine is attached to ribofuranose via a beta-N(9) glycosidic bond. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purines D-ribonucleoside and a member of inosines. It derives from a hypoxanthine and a ribofuranose.

Application

Inosine may have neuroprotective, cardioprotective, anti-inflammatory and immunomodulatory activities.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov