l General Information |
Product Name | Arbutin |
General description | Arbutin is a beta-D-glucopyranoside. It is extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family. |
Synonym | (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol; Uvasol; P-Arbutin; Ursin; Beta-Arbutin |
Purity | ≥98.0%(HPLC) | CAS Number | 497-76-7 |
Formula | C12H16O7 | Molecular Weight | 272.253 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Very slightly soluble |
Water | ≥50mg/mL |
l Biological Information |
Biochem/Physiol Actions | Arbutin is available in both natural and synthetic forms; it can be synthesized from acetobromglucose and. Arbutin is a competitive inhibitor of tyrosinase (E.C.1.14.18.1) in melanocytes, and the inhibition of melanin synthesis at non-toxic concentrations was observed in vitro. Arbutin is a tyrosinase inhibitor with an IC50 of 1.09 mM. Hydroquinone O-beta-D-glucopyranoside is a monosaccharide derivative that is hydroquinone attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic age. It has a role as a plant metabolite and an Escherichia coli metabolite. It is a beta-D-glucoside and a monosaccharide derivative. It derives from a hydroquinone. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
