l General Information |
Product Name | MitoMycin C |
General description | MitoMycin C is a methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. |
Synonym | Ametycine; Mutamycin; Mitocin-C |
Purity | ≥99.0%(HPLC) | CAS Number | 50-07-7 |
Formula | C15H18N4O5 | Molecular Weight | 334.332 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Blue-purple solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Very slightly soluble |
Water | Insolube |
l Biological Information |
Biochem/Physiol Actions | Mitomycin is a methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. Bioreduced mitomycin C generates oxygen radicals, alkylates DNA, and produces interstrand DNA cross-s, thereby inhibiting DNA synthesis. Preferentially toxic to hypoxic cells, mitomycin C also inhibits RNA and protein synthesis at high concentrations. |
Application | 1. Antibiotics, Antineoplastic 2. Cross-ing Reagents 3. Nucleic Acid Synthesis Inhibitors 4. Alkylating Agents |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
