l General Information |
Product Name | Cinnarizine |
General description | Cinnarizine is a piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces Parkinsonian disorders. |
Synonym | 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine; Stugeron |
Purity | ≥99.0%(HPLC) | CAS Number | 298-57-7 |
Formula | C26H28N2 | Molecular Weight | 368.524 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Very slightly soluble |
Water | Insolube |
l Biological Information |
Biochem/Physiol Actions | Cinnarizine is a piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces PARKINSONIAN DISORDERS. Cinnarizine is a N-alkylpiperazine. It has a role as an antiemetic, a histamine antagonist, a calcium channel blocker, a muscarinic antagonist, an anti-allergic agent and a H1-receptor antagonist. |
Application | 1. Histamine H1 Antagonists 2. Calcium Channel Blockers |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
