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LFM-A13

Product #: TL0844
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Details

l  General Information

Product Name

LFM-A13

General description

LFM-A13 is a specific Bruton's tyrosine kinase (BTK) inhibitor (IC50 = 2.5 μM).

Synonym

(Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide

Purity

≥99.0%(HPLC)

CAS Number

244240-24-2

Formula

C11H8Br2N2O2

Molecular Weight

360

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

LFM-A13 is a specific Bruton's tyrosine kinase (BTK) inhibitor with IC50 of 2.5 μM, >100-fold selectivity over other protein kinases including JAK1, JAK2, HCK, EGFR,and IRK.

l  Packaging & Storage

Packaging

5mg; 10mg

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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