l General Information |
Product Name | 3-TYP |
General description | 3-TYP is a selective SIRT3 inhibitor which is selective for Sirt3 over Sirt1 and Sirt2. |
Synonym | 3-(2H-triazol-4-yl)pyridine |
Purity | ≥99.5%(HPLC) | CAS Number | 120241-79-4 |
Formula | C7H6N4 | Molecular Weight | 146.15 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥25mg/mL |
Ethanol | ≥25mg/mL |
Water | ~5mg/mL |
l Biological Information |
Biochem/Physiol Actions | 3-TYP is a selective SIRT3 inhibitor which is selective for Sirt3 (IC50 = 16 nM) over Sirt1 (IC50 = 88 nM) and Sirt2 (IC50 = 92 nM). |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
