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Home > Products > Small molecule > Apoptosis > Salubrinal

Salubrinal

Product #: TL0835
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Details

l  General Information

Product Name

Salubrinal

General description

Salubrinal is a selective inhibitor of eIF2α dephosphorylation.

Synonym

(E)-3-phenyl-N-[2,2,2-trichloro-1-(quinolin-8-ylcarbamothioylamino)ethyl]prop-2-enamide

Purity

≥98.5%(HPLC)

CAS Number

405060-95-9

Formula

C21H17Cl3N4OS

Molecular Weight

479.81

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Light brown solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Slightly soluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM in a cell-free assay.

l  Packaging & Storage

Packaging

5mg; 10mg

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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