l General Information |
Product Name | Pifithrin-β Hydrobromide |
General description | Pifithrin-β hydrobromide is an inhibitor of p53, reversibly blocks p53-dependent transcriptional activation and apoptosis. |
Synonym | 2-(4-methylphenyl)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole; hydrobromide; Pifithrin-beta hydrobromide; Cyclic pifithrin-alpha hydrobromide |
Purity | ≥98.5%(HPLC) | CAS Number | 511296-88-1 |
Formula | C16H17BrN2S | Molecular Weight | 349.29 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥20mg/mL |
l Biological Information |
Biochem/Physiol Actions | Pifithrin-β hydrobromide is an inhibitor of p53, reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
