l General Information |
Product Name | IQ-1S |
General description | IQ-1S is an effective and specific c-Jun N-Terminal Kinase Inhibitor. |
Synonym | 11-nitroso-10H-indeno[1,2-b]quinoxaline |
Purity | ≥98.5%(HPLC) | CAS Number | 23146-22-7 |
Formula | C15H9N3O | Molecular Weight | 247.25 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥25mg/mL |
l Biological Information |
Biochem/Physiol Actions | IQ-1S is an effective and specific c-Jun N-Terminal Kinase Inhibitor. It inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
