l General Information |
Product Name | SGC 707 |
General description | SGC707 is a potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3). |
Synonym | 1-isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea; SGC707; SGC-707 |
Purity | ≥98.5%(HPLC) | CAS Number | 1687736-54-4 |
Formula | C16H18N4O2 | Molecular Weight | 298.34 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥50mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | SGC707 is a potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (IC50 = 31 nM, and Kd = 53 nM). |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
