l General Information |
Product Name | U-104 |
General description | U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII. |
Synonym | 1-(4-fluorophenyl)-3-(4-sulfamoylphenyl)urea; U 104; NSC213841 |
Purity | ≥98.5%(HPLC) | CAS Number | 178606-66-1 |
Formula | C13H12FN3O3S | Molecular Weight | 309.32 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | U-104 is a potent carbonic anhydrase inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |