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U-104

Product #: TL0815
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Details

l  General Information

Product Name

U-104

General description

U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII.

Synonym

1-(4-fluorophenyl)-3-(4-sulfamoylphenyl)urea; U 104; NSC213841

Purity

≥98.5%(HPLC)

CAS Number

178606-66-1

Formula

C13H12FN3O3S

Molecular Weight

309.32

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or Off-white solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

U-104 is a potent carbonic anhydrase inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II.

l  Packaging & Storage

Packaging

5mg; 10mg

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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