l General Information |
Product Name | GW 441756 |
General description | GW441756 is a potent, selective inhibitor of TrkA (IC50 = 2 nM), with very little activity to c-Raf1 and CDK2. |
Synonym | (3Z)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one; GW-441756; GW441756 |
Purity | ≥98.5%(HPLC) | CAS Number | 504433-23-2 |
Formula | C17H13N3O | Molecular Weight | 275.3 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Brown solid |
Solubility(25℃) | DMSO | ≥20mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | GW441756 is a potent, selective inhibitor of TrkA (IC50 = 2 nM), with very little activity to c-Raf1 and CDK2. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
