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C646

Product #: TL0805
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Details

l  General Information

Product Name

C646

General description

C646 is an inhibitor for histone acetyltransferase.

Synonym

4-[(4E)-4-[[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid

Purity

≥98.5%(HPLC)

CAS Number

328968-36-1

Formula

C24H19N3O6

Molecular Weight

445.42

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Red or dark red solid

Solubility(25℃)

DMSO

≥10mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

C646 is an inhibitor for histone acetyltransferase. It inhibits p300 with a Ki of 400 nM in a cell-free assay. Preferentially selective for p300 versus other acetyltransferases.

l  Packaging & Storage

Packaging

5mg; 10mg

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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