l General Information |
Product Name | Vatalanib (PTK787) 2HCl |
General description | Vatalanib (PTK787) 2HCl is an inhibitor of VEGFR2/KDR. |
Synonym | ZK 222584 2HCl; cpg-79787 2HCl; PTK787 2HCl |
Purity | ≥99.0%(HPLC) | CAS Number | 212141-54-3 |
Formula | C20H15ClN4·2HCl | Molecular Weight | 419.73 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Light pink solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥5mg/mL |
Water | ≥5mg/mL |
l Biological Information |
Biochem/Physiol Actions | Vatalanib (PTK787) 2HCl is an inhibitor of VEGFR2/KDR with IC50 of 37 nM in a cell-free assay,less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
