l General Information |
Product Name | CGP 57380 |
General description | CGP 57380 is a potent, selective MNK1 inhibitor. |
Synonym | 3-N-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine; CGP57380; CGP-57380 |
Purity | ≥97.0%(HPLC) | CAS Number | 522629-08-9 |
Formula | C11H9FN6 | Molecular Weight | 244.23 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Off-white or light gray solid |
Solubility(25℃) | DMSO | ≥40mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | CGP 57380 is a potent, selective MNK1 inhibitor with IC50 of 2.2 μM. It exhibits no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
