l General Information |
Product Name | Necrostatin-1 |
General description | Necrostatin-1 is a specific RIP1 inhibitor. |
Synonym | 5-(1H-indol-3-ylmethyl)-3-methyl-2-sulfanylideneimidazolidin-4-one; Necrostatin 1 |
Purity | ≥99.0%(HPLC) | CAS Number | 4311-88-0 |
Formula | C13H13N3OS | Molecular Weight | 259.33 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Yellow solid |
Solubility(25℃) | DMSO | ≥45mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Necrostatin-1, a specific RIP1 inhibitor, inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
