l General Information |
Product Name | CFTRinh-172 |
General description | CFTRinh-172 is a voltage-independent, selective CFTR inhibitor. |
Synonym | 4-[(Z)-[4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene]methyl]benzoic acid; CFTR(inh)-172; CFTR Inhibitor-172; CFTRinh 172 |
Purity | ≥99.0%(HPLC) | CAS Number | 307510-92-5 |
Formula | C18H10F3NO3S2 | Molecular Weight | 409.4 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Orange solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | CFTRinh-172 is a voltage-independent, selective CFTR inhibitor (Ki = 300 nM). It shows no effects on MDR1, ATP-sensitive K+ channels, or a series of other transporters. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
