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ML130(Nodinitib-1)

Product #: TL0782
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Details

l  General Information

Product Name

ML130(Nodinitib-1)

General description

ML130 (Nodinitib-1) is a potent and selective inhibitor.

Synonym

1-(4-methylphenyl)sulfonylbenzimidazol-2-amine; ML-130; ML 130; Nodinitib 1

Purity

≥99.0%(HPLC)

CAS Number

799264-47-4

Formula

C14H13N3O2S

Molecular Weight

287.34

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or Off-white solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Slightly soluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

ML130 (Nodinitib-1) is a potent and selective inhibitor of NOD1 (IC50 = 0.56 μM). It inhibits NF-κB activation, exhibits 36-fold selectivity over NOD2.

l  Packaging & Storage

Packaging

5mg; 10mg

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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