l General Information |
Product Name | ML130(Nodinitib-1) |
General description | ML130 (Nodinitib-1) is a potent and selective inhibitor. |
Synonym | 1-(4-methylphenyl)sulfonylbenzimidazol-2-amine; ML-130; ML 130; Nodinitib 1 |
Purity | ≥99.0%(HPLC) | CAS Number | 799264-47-4 |
Formula | C14H13N3O2S | Molecular Weight | 287.34 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Slightly soluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | ML130 (Nodinitib-1) is a potent and selective inhibitor of NOD1 (IC50 = 0.56 μM). It inhibits NF-κB activation, exhibits 36-fold selectivity over NOD2. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
