l General Information |
Product Name | PD-166866 |
General description | PD-166866 is a selective inhibitor of FGFR1. |
Synonym | 1-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea; PD 166866; PD166866 |
Purity | ≥99.0%(HPLC) | CAS Number | 192705-79-6 |
Formula | C20H24N6O3 | Molecular Weight | 396.44 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥10mg/mL |
Ethanol | Slightly soluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | PD-166866, a synthetic molecule, inhibits the tyrosin kinase action of FGFR1, shows a very high selectivity towards FGFR1 and inhibits the auto-phosphorylation activity of FGRF1. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
