l General Information |
Product Name | 10074-G5 |
General description | 10074-G5, a c-Myc inhibitor, binds to and distorts the bHLH-ZIP domain of c-Myc, thereby inhibiting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity. |
Synonym | 4-nitro-N-(2-phenylphenyl)-2,1,3-benzoxadiazol-7-amine |
Purity | ≥97.0%(HPLC) | CAS Number | 413611-93-5 |
Formula | C18H12N4O3 | Molecular Weight | 332.31 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Brown or dark borwn solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥50mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | 10074-G5 is a c-Myc inhibitor that binds to and distorts the bHLH-ZIP domain of c-Myc with Kd values of 2.8 µM, thereby inhibiting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity with IC50 values of 146 µM. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
