l General Information |
Product Name | Dapivirine |
General description | Dapivirine, a non-nucleoside inhibitor for HIV reverse transcriptase, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. |
Synonym | 4-[[4-(2,4,6-trimethylanilino)pyrimidin-2-yl]amino]benzonitrile; TMC120; TMC 120 |
Purity | ≥99.0%(HPLC) | CAS Number | 244767-67-7 |
Formula | C20H19N5 | Molecular Weight | 329.4 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥30mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase (IC50 = 24 nM). It inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI resistant isolates. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
