l General Information |
Product Name | Molidustat (BAY85-3934) |
General description | Molidustat (BAY 85-3934) is a potent hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor. |
Synonym | 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(triazol-1-yl)-1H-pyrazol-3-one; BAY 85-3934; BAY-85-3934 |
Purity | ≥99.0%(HPLC) | CAS Number | 1154028-82-6 |
Formula | C13H14N8O2 | Molecular Weight | 314.3 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Light pink solid |
Solubility(25℃) | DMSO | Slightly soluble |
DMF | ≥4mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Molidustat (BAY 85-3934) is a potent hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor with IC50 of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD, respectively. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
