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Molidustat (BAY85-3934)

Product #: TL0772
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Details

l  General Information

Product Name

Molidustat (BAY85-3934)

General description

Molidustat (BAY 85-3934) is a potent hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor.

Synonym

2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(triazol-1-yl)-1H-pyrazol-3-one; BAY 85-3934; BAY-85-3934

Purity

≥99.0%(HPLC)

CAS Number

1154028-82-6

Formula

C13H14N8O2

Molecular Weight

314.3

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Light pink solid

Solubility(25℃)

DMSO

Slightly soluble

DMF

≥4mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

Molidustat (BAY 85-3934) is a potent hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor with IC50 of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD, respectively.

l  Packaging & Storage

Packaging

5mg; 10mg

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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