l General Information |
Product Name | Serabelisib(INK-1117) |
General description | Serabelisib is a potent and selective oral PI3Kα isoform inhibitor. |
Synonym | [6-(2-amino-1,3-benzoxazol-5-yl)imidazo[1,2-a]pyridin-3-yl]-morpholin-4-ylmethanone; TAK-117; MLN-1117; MLN1117 |
Purity | ≥97.0%(HPLC) | CAS Number | 1268454-23-4 |
Formula | C19H17N5O3 | Molecular Weight | 363.37 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Brown solid |
Solubility(25℃) | DMSO | ≥16mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Serabelisib is a potent and selective oral PI3Kα isoform inhibitor (IC50 = 21 nM). It has demonstrated > 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
