l General Information |
Product Name | PRT 4165 |
General description | PRT 4165 is a Bmi1/Ring1A inhibitor, also inhibits PRC1-mediated H2A ubiquitylation in vivo and in vitro. |
Synonym | 2-(pyridin-3-ylmethylidene)indene-1,3-dione; PRT-4165; PRT4165 |
Purity | ≥99.0%(HPLC) | CAS Number | 31083-55-3 |
Formula | C15H9NO2 | Molecular Weight | 235.24 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Yellow or khaki solid |
Solubility(25℃) | DMSO | ≥10mg/mL |
Ethanol | ~5mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | PRT4165 is a Bmi1/Ring1A inhibitor with an IC50 of 3.9 µM in the cell-free assay and also inhibits PRC1-mediated H2A ubiquitylation in vivo and in vitro. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
