l General Information |
Product Name | SBE 13 hydrochloride |
General description | SBE 13 hydrochloride is a potent and selective PLK1 inhibitor. |
Synonym | N-[[4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl]methyl]-2-(3,4-dimethoxyphenyl)ethanamine; hydrochloride |
Purity | ≥99.0%(HPLC) | CAS Number | 1052532-15-6 |
Formula | C24H28Cl2N2O4 | Molecular Weight | 479.4 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | SBE 13 HCl is a potent and selective PLK1 inhibitor (IC50 = 200 pM), >4000-fold selectivity over Aurora A kinase, Plk2 and Plk3. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
