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IM-12

Product #: TL0736
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Details

l  General Information

Product Name

IM-12

General description

IM-12 is a selective GSK-3β inhibitor and also enhances canonical Wnt signalling.

Synonym

3-[2-(4-fluorophenyl)ethylamino]-1-methyl-4-(2-methyl-1H-indol-3-yl)pyrrole-2,5-dione

Purity

≥98.5%(HPLC)

CAS Number

1129669-05-1

Formula

C22H20FN3O2

Molecular Weight

377.41

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Yellow solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

≥5mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

IM-12 is a selective GSK-3β inhibitor (IC50 = 53 nM), and also enhances canonical Wnt signalling.

l  Packaging & Storage

Packaging

5mg; 10mg

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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