l General Information |
Product Name | IM-12 |
General description | IM-12 is a selective GSK-3β inhibitor and also enhances canonical Wnt signalling. |
Synonym | 3-[2-(4-fluorophenyl)ethylamino]-1-methyl-4-(2-methyl-1H-indol-3-yl)pyrrole-2,5-dione |
Purity | ≥98.5%(HPLC) | CAS Number | 1129669-05-1 |
Formula | C22H20FN3O2 | Molecular Weight | 377.41 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Yellow solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥5mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | IM-12 is a selective GSK-3β inhibitor (IC50 = 53 nM), and also enhances canonical Wnt signalling. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |