l General Information |
Product Name | Reversine |
General description | Reversine is a potent human A3 adenosine receptor antagonist, and a pan-aurora A/B/C kinase inhibitor. Also used for stem cell dedifferentiation. |
Synonym | 6-N-cyclohexyl-2-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine |
Purity | ≥96.0%(HPLC) | CAS Number | 656820-32-5 |
Formula | C21H27N7O | Molecular Weight | 393.23 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Off-white or gray solid |
Solubility(25℃) | DMSO | ~5mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Reversine is a potent human A3 adenosine receptor antagonist (Ki = 0.66 μM), and a pan-aurora A/B/C kinase inhibitor (IC50 = 12 nM/13 nM/20 nM, respectively). Also used for stem cell dedifferentiation. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
