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SMI-4a

Product #: TL0733
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Details

l  General Information

Product Name

SMI-4a

General description

SMI-4a is a potent inhibitor of Pim1, modestly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases.

Synonym

(5Z)-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione; TCS PIM-1 4a

Purity

≥99.0%(HPLC)

CAS Number

438190-29-5

Formula

C11H6F3NO2S

Molecular Weight

273.23

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or Off-white solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

≥30mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

SMI-4a is a potent inhibitor of Pim1 (IC50 = 17 nM), modestly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases.

l  Packaging & Storage

Packaging

5mg; 10mg

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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