l General Information |
Product Name | SMI-4a |
General description | SMI-4a is a potent inhibitor of Pim1, modestly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases. |
Synonym | (5Z)-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione; TCS PIM-1 4a |
Purity | ≥99.0%(HPLC) | CAS Number | 438190-29-5 |
Formula | C11H6F3NO2S | Molecular Weight | 273.23 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥30mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | SMI-4a is a potent inhibitor of Pim1 (IC50 = 17 nM), modestly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases. |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
