Product Name

Natamycin

General description

Natamycin is a polyene amphoteric macrolide antibiotic with antifungal properties.

Synonym

Pimaricin; Tennecetin

Assay

90.0% ~ 102.0% (calculated on the anhydrous basis)

CAS Number

7681-93-8

Formula

C33H47NO13

Molecular Weight

665.73

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or Off-white solid

Solubility(25℃)

DMSO

≥5mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

Natamycin is a polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect.

Application

1.     Antifungal Agents

2.     Anti-Bacterial Agents

3.     Anti-Infective Agents, Local

l  Packaging & Storage

Packaging

50mg; 250mg

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov