l General Information |
Product Name | Clozapine |
General description | Clozapine is a synthetic dibenzo-diazepine derivative, atypical antipsychotic. |
Synonym | 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]-diazepine; Leponex; Clozapin |
Purity | ≥99.0%(HPLC) | CAS Number | 5786-21-0 |
Formula | C18H19ClN4 | Molecular Weight | 326.828 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Yellow solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥30mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Clozapine is a synthetic dibenzo-diazepine derivative, atypical antipsychotic Clozapine blocks several neurotransmitter receptors in the brain (dopamine type 4, serotonin type 2, norepinephrine, acetylcholine, and histamine receptors). Unlike traditional antipsychotic agents, it weakly blocks dopamine type 2 receptors. It relieves schizophrenic symptoms (hallucinations, delusions, dementia). |
Application | 1. Antipsychotic Agents 2. Serotonin Antagonists 3. GABA Antagonists |
l Packaging & Storage |
Packaging | 250mg; 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
