l General Information |
Product Name | Acarbose |
General description | Acarbose is a pseudotetrasaccharide and inhibitor of alpha-glucosidase and pancreatic alpha amylase with antihyperglycemic activity. |
Synonym | 4",6"-Dideoxy-4"-([1S]-[1,4,6/5]-4,5,6-trihydroxy-3-hydroxymethyl-2-yclohexenylamino)-maltotriose |
Purity | ≥98.0%(HPLC) | CAS Number | 56180-94-0 |
Formula | C25H43NO18 | Molecular Weight | 645.60 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥5mg/mL |
Water | ≥50mg/mL |
l Biological Information |
Biochem/Physiol Actions | Acarbose is a pseudotetrasaccharide and inhibitor of alpha-glucosidase and pancreatic alpha amylase with antihyperglycemic activity. Acarbose binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. In addition, acarbose inhibits pancreatic alpha-amylase which hydrolyzes complex starches to oligosaccharides in the small intestines. |
Application | Glycoside Hydrolase Inhibitors |
l Packaging & Storage |
Packaging | 250mg; 1g |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
