l General Information |
Product Name | Cefuroxime Sodium |
General description | Cefuroxime Sodium is a semi-synthetic, broad-spectrum, beta-lactamase resistant, second generation cephalosporin antibiotic with bactericidal activity. |
Synonym | sodium;(6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Kefurox |
Purity | ≥98.0%(HPLC) | CAS Number | 56238-63-2 |
Formula | C16H15N4NaO8S | Molecular Weight | 446.37 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Pale yellow or yellow solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | ≥50mg/mL |
l Biological Information |
Biochem/Physiol Actions | Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-ing of peptidoglycan units which are a component of the cell wall. Lack of cross-ing results in a reduction of cell wall stability and leads to cell lysis. |
Application | Anti-Bacterial Agents |
l Packaging & Storage |
Packaging | 250mg; 1g |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |