Product Name

Cefprozil

General description

Cefprozil is a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.

Synonym

(6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(E)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefprozilum; Cefprozil anhydrous

Purity(HPLC)

≥98%(Cefprozil (Z)-Isomer + Cefprozil (E)-Isomer);

(E)-isomer ratio=(E/(E+Z)), the ratio is between 0.06 and 0.11;

CAS Number

92665-29-7

Formula

C¹⁸H¹⁹N³O⁵S

Molecular Weight

389.43

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Off-white or pale yellow solid

Solubility(25℃)

DMSO

≥25mg/mL

Ethanol

≥10mg/mL

Water

Slightly soluble

l  Biological Information

Biochem/Physiol   Actions

Cefprozil is a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefprozil's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in   the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-ing of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefprozil inhibits bacterial septum and cell wall synthesis formation.

Application

Anti-Bacterial Agents

l  Packaging & Storage

Packaging

25mg; 100mg; 250mg

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov