l General Information |
Product Name | Oxcarbazepine |
General description | Oxcarbazepine is a dibenzazepine carboxamide derivative with an anticonvulsant property. |
Synonym | 10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide; GP47680 |
Purity | ≥99.0%(HPLC) | CAS Number | 28721-07-5 |
Formula | C15H12N2O2 | Molecular Weight | 252.27 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥5mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Oxcarbazepine is a dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses. |
Application | 1. Voltage-Gated Sodium Channel Blockers 2. Cytochrome P-450 CYP3A Inducers 3. Anticonvulsants |
l Packaging & Storage |
Packaging | 1g; 5g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
