l General Information |
Product Name | Risperidone |
General description | Risperidone is a selective blocker of Dopamine D2 receptors and Serotonin 5-HT2 receptors that acts as an atypical antipsychotic agent. |
Synonym | 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2 a]pyrimidin-4-one; R-64766 |
Purity | ≥99.0%(HPLC) | CAS Number | 106266-06-2 |
Formula | C23H27FN4O2 | Molecular Weight | 410.48 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | Slightly soluble |
Ethanol | Slightly soluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Risperidone is a benzisoxazole derivative with antipsychotic property. Risperidone selectively antagonizes serotonin (5-HT) effects via cortical 5-HT2 receptor, and, to a lesser extent, competes with dopamine at the limbic dopamine D2 receptor. The antagonism leads to decreased psychotic effects, such as hallucinations and delusions. In addition, risperidone has low to moderate affinity for histamine H1, 5-HT1A, 5-HT1C, and 5-HT1D receptors, while it has weak affinity for dopamine D1 and haloperidol-sensitive sigma site receptors. |
Application | 1. Antipsychotic Agents 2. Dopamine Antagonists 3. Serotonin Antagonists |
l Packaging & Storage |
Packaging | 250mg; 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
