l General Information |
Product Name | Diethylstilbestrol |
General description | Diethylstilbestrol is a synthetic, nonsteroidal form of estrogen. |
Synonym | (E)-3,4-Bis(4-hydroxyphenyl)-3-hexene; DES; Stilbestrol |
Purity | ≥98.0%(HPLC) | CAS Number | 56-53-1 |
Formula | C18H20O2 | Molecular Weight | 268.35 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥50mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Diethylstilbestrol is a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. |
Application | 1. Carcinogens Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. 2. Estrogens, Non-Steroidal Non-steroidal compounds with estrogenic activity. |
l Packaging & Storage |
Packaging | 50mg; 250mg; 1g |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
