l General Information |
Product Name | Abacavir sulfate |
General description | Abacavir sulfate is a nucleoside analogue and reverse transcriptase inhibitor. |
Synonym | (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol sulfate |
Purity | ≥98.0%(HPLC) | CAS Number | 188062-50-2 |
Formula | C28H38N12O6S | Molecular Weight | 670.75 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or almost white solid |
Solubility(25℃) | DMSO | Very slightly soluble |
Ethanol | Very slightly soluble |
Water | ≥30mg/mL |
l Biological Information |
Biochem/Physiol Actions | Abacavir Sulfate is a sulfate salt form of abacavir, a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS. |
Application | 1. Reverse Transcriptase Inhibitors Inhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template. 2. Anti-HIV Agents Agents used to treat AIDS and/or stop the spread of the HIV infection. These do not include drugs used to treat symptoms or opportunistic infections associated with AIDS. |
l Packaging & Storage |
Packaging | 50mg; 250mg; 1g |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
