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Vonoprazan fumarate

Product #: TL0497
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Details

l  General Information

Product Name

Vonoprazan fumarate

General description

Vonoprazan Fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase, controls gastric acid secretion.

Synonym

(E)-but-2-enedioic acid; 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine; TAK-438

Purity

≥99.0%(HPLC)

CAS Number

1260141-27-2

Formula

C21H20FN3O6S

Molecular  Weight

461.46

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or Off-white solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Very slightly soluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

Vonoprazan Fumarate is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase, controls gastric acid secretion.

Application

Vonoprazan has been used in trials studying the treatment of Erosive Esophagitis.

l  Packaging & Storage

Packaging

25mg; 250mg; 1g

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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