Product Name

Carbamazepine

General description

Carbamazepine is a tricyclic compound chemically related to tricyclic antidepressants  with anticonvulsant and analgesic properties.

Synonym

benzo[b][1]benzazepine-11-carboxamide; NSC169864

Purity

≥99.0%(HPLC)

CAS Number

298-46-4

Formula

C¹⁵H¹²N²O

Molecular Weight

236.27

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or almost white solid

Solubility(25℃)

DMSO

≥40mg/mL

Ethanol

≥15mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

Carbamazepine is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysynaptic responses and blocking post-tetanic potentiation. Its analgesic activity is not understood; however, carbamazepine is commonly used to treat pain associated with trigeminal neuralgia.

Application

1.    Anticonvulsants

Drugs used to prevent seizures or reduce their severity.

2.    Analgesics, Non-Narcotic

A subclass of analgesic agents that typically do not bind to opioid receptors and are not addictive. Many non-narcotic analgesics are offered as nonprescription drugs.

3.    Cytochrome P-450 CYP3A Inducers

Drugs and compounds that induce the synthesis of Cytochrome P-450 CYP3A.

4.    Antimanic Agents

Agents that are used to treat bipolar disorders or mania associated with other affective disorders.

l  Packaging & Storage

Packaging

1g; 5g

Storage temp.

0-5℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov